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General information. Leukeran belongs to the group of medications known as antineoplastics. It contains chlorambucil. This medication works by preventing the growth of cancer cells by interfering with the genetic material DNA, which is necessary for reproduction of cells. Leukeran is used to treat certain types of cancer (leukemia, lymphoma, Hodgkin's disease). This drug may also be used for certain blood diseases, certain types of kidney disease in children that have not responded to other treatment.
Directions. Take Leukeran exactly as prescribed by your doctor. Take this medication by mouth. Drink plenty of fluids while taking this medication to prevent side effects. For chronic lymphocytic leukemia, the usual adult starting dose is 0.15 mg per kilogram body weight per day until the total white blood cell count reaches the desired range. 4 weeks after the first course of treatment, the medication may be restarted at a dose of 0.1 mg per kilogram body weight per day. For Hodgkin's disease, the usual dose is 0.2 mg per kilogram body weight per day for 4 to 8 weeks. For non-Hodgkin's lymphoma, the usual dose is 0.1 mg to 0.2 mg per kilogram body weight per day for 4 to 8 weeks initially.
Overdose. If you think you have overdosed the medicine seek emergency medical help at once. The overdose symptoms are loss of balance, excitation, convulsions.
Leukeran is a cancer medication which is used to treat certain types of cancer (leukemia, lymphoma, Hodgkin's disease).
Contraindications. Do not take Leukeran if you are allergic to chlorambucil or any ingredients of this medication, are pregnant or breastfeeding, or if you have had a full course of radiation or chemotherapy within the previous 4 weeks.
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